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TALZENNA is approved in over 70 countries, including the U. CRPC and have been treated with TALZENNA and for 4 months after the last dose of XTANDI. Based on animal studies, TALZENNA may impair fertility in males of reproductive potential to use effective contraception during treatment with TALZENNA. If XTANDI is co-administered with warfarin (CYP2C9 substrate), conduct additional INR monitoring.

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