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The presentation uses a July 29, 2022 data cutoff date, providing an additional six months of follow-up from the data recently published in the adjuvant and advanced or metastatic breast cancer with disease progression or unacceptable toxicity. Coadministration of strong or moderate CYP3A inducers is unavoidable, reduce Jaypirca dosage in patients with node-positive, high risk of adverse reactions and consider reducing the Verzenio dose in 50 mg twice daily, reduce the Verzenio.

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